The DoD Small Business and Technology Partnerships Office announces the opening of the following Broad Agency Announcement (BAA) topic:

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  27 octobre 2020 | International, Aérospatial, C4ISR

  Lockheed Seeks Commercial Tie-Ups to Chase 5G Work

  CEO Taiclet wants a leading role as U.S. and allied militaries build out their next-gen mobile networks. Marcus Weisgerber Commercial partnerships will be key as Lockheed Martin seeks to help U.S. and allied militaries move to 5G networking — and diversify its offerings beyond fighter jets and missiles, its CEO said in an interview this week. “I think, an imperative that we Lockheed Martin, and frankly the defense industrial base, partner with [the] commercial industry to accelerate the benefits of what I call 21st-century technologies into the defense [industrial] base, and into our national defense,” Jim Taiclet said in an Oct. 20 interview after his company’s 3rd-quarter earnings call.  A former telecom executive, Taiclet took the reins at the world’s largest defense contractor in June amid an increased push by the Pentagon leaders to better connect the military’s weapons, regardless of manufacturer, so they can more quickly share information on the battlefield. The Air Force alone plans to spend at least $9 billion over the next five years connecting its weapons through an initiative known as Combined Joint All Domain Command and Control. The Pentagon is conducting increasingly ambitious experiments with 5G wireless technology, which promises to link weapons with such high data-transfer rates that military commanders will be able to make decisions faster and with more information. “We're interested in operationalizing the technical capabilities of 5G waveforms and technology software and hardware to improve our defense products and our defense products' performance in an interrelated way,” Taiclet said Tuesday on the company’s third-quarter earning call with Wall Street analysts. The Pentagon has been increasingly embracing commercial firms like Amazon Web Services and Microsoft as the military shifts to the cloud. It’s also been on a half-decade push to get more commercial tech firms to embrace defense work, which has been a bumpy relationship at times. Taiclet said the company would pursue partnerships not just in 5G, but also artificial intelligence, edge computing, autonomy, and additive manufacturing. “I think there's some incredible runway or open space there for us to be a leader in bringing some of those companies and some of those technology leaders in partnership with us,” Taiclet said in the interview.  He raised the prospect of forming alliances or licensing commercial technology from telecom firms like Qualcomm, NextCom or Nokia. He also said the company could form joint ventures with commercial tech firms. It could include buying companies too.  “We're just gonna open our aperture wider,” Taiclet said. “And we also want to get more active and mission systems too. So, we'll see what's available in that space as well ... closer to the home base here. I think there's a lot of optionality for us going forward.” On the earnings call, Taiclet also suggested Lockheed could offer “networking as a service, more of a subscription model” to the military. “Then we do the upgrades and the comm layer and make sure we tie it all together, just like you experience on your cellphone subscription,” he said. You don't know all the pieces that go into it. So every morning when you turn it on, it works and it works with the latest applications, and it works with the latest technology.  “Those are the kinds of things we're going to explore,” he said. “It will take a little bit longer to get there, but we're positioning ourselves to do that as well.” https://www.defenseone.com/business/2020/10/lockheed-seeks-commercial-tie-ups-chase-5g-work/169566/

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  30 novembre 2018 | International,

  Reinventing Drug Discovery and Development for Military Needs

  Flying at 50,000 feet, diving deep in the ocean, or hiking for miles with gear through extreme climates, military service members face conditions that place unique burdens on their individual physiology. The potential exists to develop pharmacological interventions to help service members complete their toughest missions more safely and efficiently, and then recover more quickly and without adverse effects, but those interventions must work on complex physiological systems in the human body. They will not be realized under the prevailing system of drug discovery and development with its focus on engaging single molecular targets. DARPA created the Panacea program to pursue the means of rapidly discovering, designing, and validating new, multi-target drugs that work with the body’s complexity to better support the physiological resilience and recovery of military service members. The premise of Panacea is that the physiological systems of the human body work in complex and highly integrated ways. Drugs exert effects on our bodies by physically interacting with and changing the functional state of biomolecules that govern the functions of cells and tissues. Most drugs target proteins, which are the principle cellular workhorses. Ideally, drugs would target multiple proteins simultaneously to exert precise, network-level effects. One major problem facing the drug development community is that the functional proteome — the complete collection of proteins and their roles in signaling networks — is largely dark to science. Despite being able to identify many of the proteins within a cell, researchers do not have a firm grasp on everything those proteins do and how they interact to affect physiology. Due to this sparsity of structural and functional knowledge, the state of the art in drug development — what Panacea seeks to transform — is to engage only a very small fraction of known protein targets to achieve an effect. In fact, today’s approach to drug design singles out individual proteins in certain cells. That hyper-specificity is an attempt to minimize the risk of side effects and speed time to market, but it also yields a thin stream of drugs, many of which have similar mechanisms and relatively muted effectiveness compared to what might be achieved using a multi-target, systems-based approach. “The current roster of drugs approved by the U.S. Food and Drug Administration only targets about 549 proteins, yet the body can produce more than six million different protein variants,” said Tristan McClure-Begley, the Panacea program manager. “The opportunity space for pharmacological intervention is vast and effectively untapped, but to access it we need new technology for understanding and targeting the human functional proteome.” Panacea will address the lack of functional knowledge about the proteome. DARPA’s call to the research community is to consider complex physiological conditions relevant to military service members — for instance, metabolic stress during extreme endurance missions or pain and inflammation after injury; investigate the molecular mechanisms underlying those conditions; identify multiple, key molecular targets involved; and develop novel medicinal chemistry approaches to synthesize interventions that modulate those targets. DARPA believes that multi-target drugs will deliver safer and more efficacious solutions to military requirements for readiness and recovery over state-of-the-art interventions. “Many of the most successful drugs produced in the past were found rather than made, and we knew what they did long before we knew how they did it,” McClure-Begley said. “To deliver improved interventions, we need to get to a place where we can investigate all of the potential proteins at play for a given condition and then prioritize sets of protein targets and signaling networks to effectively modulate physiological systems, regardless of what prior knowledge exists about those targets.” The Panacea program aims to generate initial proof of concept for this new direction in drug discovery and development. Research will primarily involve animal models, human cell derived organoids, and high-throughput cell culture models. However, to support eventual transition to humans, DARPA will work with federal agencies to develop a regulatory pathway for future medical use. By the end of the five-year program, DARPA will require teams to submit novel drug candidates to the U.S. Food and Drug Administration for review as an Investigational New Drug or for Compassionate Use. DARPA will hold a Proposers Day on December 14, 2018, in Arlington, Virginia, to provide more information about Panacea and answer questions from potential proposers. For details of the event, including registration requirements, visit https://go.usa.gov/xP6hD. A forthcoming Broad Agency Announcement will fully describe the program structure and objectives. https://www.darpa.mil/news-events/2018-11-28

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  8 août 2019 | International, Sécurité

  The Air Force sends good guys in to hack its cloud

  By: Andrew Eversden The Air Force invited ethical hackers into its IT networks again this spring, allowing good guys the chance to infiltrate its enterprise-wide Air Force Common Computing Environment in search of vulnerabilities, the white hat hacking company Bugcrowd announced Aug. 6. The bug bounty program, done in a partnership with Bugcrowd and the Air Force’s CCE program office, found 54 vulnerabilities. Bug bounties work under the assumption that the customer, in this case the Air Force, will now close the loopholes the hackers found, making the system more secure. The CCE cloud uses Amazon Web Services and Microsoft’s Azure commercial cloud. The service plans to migrate more than 100 applications to that cloud environment, Bugcrowd executives said. The largest payout from the bug bounty totaled $20,000. The event ran from March 18 to June 21 at Hanscom Air Force Base in Massachusetts. Casey Ellis, Bugcrowd founder and CTO, said it was the first time Bugcrowd has worked with the Air Force. The Air Force has completed several other white hat hacking events with the firm HackerOne. Ellis said that moving to the cloud from on-premise environment represents a “paradigm shift” for many organizations. Penetration testing is an important part of keeping that environment secure, he said. Bugcrowd conducted such tests in six phases: source code analysis, AWS environment testing, Azure environment testing, black box network authentication assessment, social engineering engagement and Air Force portal testing. Bugcrowd declined to discuss how many vulnerabilities were found throughout each stage of the process. According to a news release from the Air Force from April, the CCE currently houses 21 Air Force applications and "has room for countess more.” The computing environment allows the Air Force to have a cloud to host its applications that reside on its Global Combat Support System, which is a centralized, cohesive enterprise resource planning system. The Air Force said in the April release that each migration costs $446,000 and that the service has spent more than $136 million on the program since 2016. https://www.fifthdomain.com/dod/air-force/2019/08/06/the-air-force-sends-good-guys-in-to-hack-its-cloud/