September 11, 2023 | International, Naval
Norway orders additional Naval Strike Missile
The value of the contract is MNOK 487.
February 7, 2019 | International, Security, Other Defence
DARPA: Intelligent Healing for Complex Wounds
Blast injuries, burns, and other wounds experienced by warfighters often catastrophically damage their bones, skin, and nerves, resulting in months to years of recovery for the most severe injuries and often returning imperfect results. This long and limited healing process means prolonged pain and hardship for the patient, and a drop in readiness for the military. However, DARPA believes that recent advances in biosensors, actuators, and artificial intelligence could be extended and integrated to dramatically improve tissue regeneration. To achieve this, the new Bioelectronics for Tissue Regeneration (BETR) program asks researchers to develop bioelectronics that closely track the progress of the wound and then stimulate healing processes in real time to optimize tissue repair and regeneration.
Paul Sheehan, the BETR program manager, described his vision for the technology as “not just personalized medicine, but dynamic, adaptive, and precise human therapies” that adjust to the wound state moment by moment to provide greater resilience to wounded warfighters.
“Wounds are living environments and the conditions change quickly as cells and tissues communicate and attempt to repair,” Sheehan said. “An ideal treatment would sense, process, and respond to these changes in the wound state and intervene to correct and speed recovery. For example, we anticipate interventions that modulate immune response, recruit necessary cell types to the wound, or direct how stem cells differentiate to expedite healing.”
The envisioned BETR technology would represent a sharp break from traditional wound treatments, and even from other emerging technologies to facilitate recovery, most of which are passive in nature.
Under current medical practice, physicians provide the conditions and time for the body to either heal itself when tissues have regenerative capacity or to accept and heal around direct transplants. Most people are familiar with interventions that include casts to stabilize broken bones or transplants of healthy ligaments or organs from donors to replace tissues that do not regenerate.
Passive approaches often result in slow healing, incomplete healing with scarring, or, in some unfortunate cases, no healing at all. Blast injuries in particular seem to scramble the healing processes; 23 percent of them will not fully close. Moreover, research shows that in nearly two thirds of military trauma cases — a rate far higher than with civilian trauma injuries — these patients suffer abnormal bone growth in their soft tissue due to a condition known as heterotopic ossification, a painful experience that can greatly limit future mobility.
Although recent experimental treatments offer some hope for expedited recovery, many of these new approaches remain static in nature. For instance, some “smart” bandages emit a continuous weak electric field or locally deliver drugs. Alternatively, hydrogel scaffolds laced with a drug can recruit stem cells, while decellularized tissue re-seeded with donor cells from the patient help avoid rejection by the host's immune system. These newer approaches may indeed encourage growth of otherwise non-regenerative tissue, but because they do not adapt to the changing state of a wound, their impact is limited.
“To understand the importance of adaptive treatments that respond to the wound state, consider the case of antibiotic ointments,” Sheehan explained. “People use antibiotics to treat simple cuts, and they help if the wound is infected. However, completely wiping out the natural microbiota can impair healing. Thus, without feedback, antibiotics can become counterproductive.”
Recent technologies have begun to close the loop between sensing and intervention, looking for signs of infection such as changes in pH level or temperature to trigger treatment. To date, however, these systems have been limited to monitoring changes induced by bacteria. For BETR, DARPA intends to use any available signal, be it optical, biochemical, bioelectronic, or mechanical, to directly monitor the body's physiological processes and then to stimulate them to bring them under control, thereby speeding healing or avoiding scarring or other forms of abnormal healing.
By the conclusion of the four-year BETR program, DARPA expects researchers to demonstrate a closed-loop, adaptive system that includes sensors to assess wound state and track the body's complex responses to interventions; biological actuators that transmit appropriate biochemical and biophysical signals precisely over space and time to influence healing; and adaptive learning approaches to process data, build models, and determine interventions. To succeed, the BETR system must yield faster healing of recalcitrant wounds, superior scar-free healing, and/or the ability to redirect abnormally healing wounds toward a more salutary pathway.
DARPA anticipates that successful teams will include expertise in bioelectronics, artificial intelligence, biosensors, tissue engineering, and cellular regeneration. Further, DARPA encourages proposals that address healing following osseointegration surgery, which is often necessary to support the use of advanced prosthetics by wounded warfighters.
DARPA will host a Proposers Day on March 1, 2019 in Arlington, Virginia, to provide more information to researchers interested in submitting a proposal for funding. Additional information is available at https://go.usa.gov/xENCQ. A forthcoming Broad Agency Announcement, to be posted to the Federal Business Opportunities website, will include full details of the program.
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March 26, 2019 | International, Aerospace
Le marché français de la défense aiguise l'appétit du suédois Saab
Le systémier Saab cherche à placer ses moyens de guerre électronique en France, notamment auprès d'Airbus Helicopters et de Dassault aviation. [...] https://www.lalettrea.fr/entreprises_defense-et-aeronautique/2019/03/20/le-marche-francais-de-la-defense-aiguise-l-appetit-du-suedois-saab,108349684-brl
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February 25, 2019 | International, Aerospace, Naval, Land, C4ISR, Security, Other Defence
Contract Awards by US Department of Defense - February 19, 2019
AIR FORCE United Launch Services, Centennial, Colorado, has been awarded a $441,761,778 firm-fixed-price contract, for launch services to deliver the SILENTBARKER, SBIRS GEO-5, and SBIRS GEO-6 missions to their intended orbits. This launch service contract will include launch vehicle production, mission integration, mission launch operations/spaceflight worthiness, and mission unique activities for SILENTBARKER and SBIRS GEO-5, with an option for an additional SBIRS GEO-6 launch service. The locations of performance are Centennial, Colorado; and Cape Canaveral, Florida. SILENTBARKER is expected to be completed by March 2022, SBIRS GEO-5 is expected to be completed by March 2021. This award is the result of a competitive acquisition and two offers were received. Fiscal 2018 and 2019 space procurement funds in the amount of $308,550,970 will be obligated at the time of award. The Contracting Division, Launch Systems Enterprise Directorate, Space and Missile Systems Center, Los Angeles Air Force Base, El Segundo, California, is the contracting activity (FA8811-19-C-0005). Space Exploration Technologies Corp., Hawthorne, California, has been awarded a $297,000,000 firm-fixed-price contract, for launch services to deliver the NROL-87, NROL-85, and AFSPC-44 missions to their intended orbits. This launch service contract will include launch vehicle production, mission integration, mission launch operations/spaceflight worthiness and mission unique activities for each mission. The locations of performance are Hawthorne, California; Cape Canaveral Air Force Space Station, Florida; and Vandenberg Air Force Base, California. NROL-85 and NROL-87 are expected to be completed by December 2021 and AFSPC-44 is expected to be completed by February 2021. This award is the result of a competitive acquisition and two offers were received. Fiscal 2018 and 2019 space procurement funds in the amount of $285,223,097 will be obligated at the time of award. The Contracting Division, Launch Systems Enterprise Directorate, Space and Missile Systems Center, Los Angeles Air Force Base, El Segundo, California, is the contracting activity (FA8811-19-C-0004). NAVY Marine Systems Corp., Boston, Massachusetts, is awarded a $29,111,774 indefinite-delivery/indefinite-quantity, cost-plus-fixed-fee, firm-fixed-price hybrid single award contract for engineering, logistical, and information technology services to support the Navy Habitability Projects. The contract will include a five-year base ordering period with a six-month ordering period option pursuant of Federal Acquisition Regulation 52.212-8 - option to extend services, which if exercised, will bring the total ceiling value to $32,191,928. Work will be performed in Norfolk, Virginia (84 percent); San Diego, California (5 percent); Pearl Harbor, Hawaii (5 percent); Mayport, Florida (2 percent); Washington, District of Columbia (1 percent); Bahrain (1 percent); Japan (1 percent); and Rota, Spain (1 percent). The base ordering period is expected to be completed by March 2024; if the option is exercised, the ordering period will be completed by August 2024. Fiscal 2019 operations and maintenance (Navy) funds in the amount of $25,000 will be obligated to fund the contract's minimum amount and funds will expire at the end of the current fiscal year. This contract was competitively procured with the solicitation posted to the Federal Business Opportunities and Navy Electronic Commerce Online websites, with five offers received. Naval Supply Systems Command Fleet Logistics Center Norfolk, Contracting Department Norfolk Office, Norfolk, Virginia, is the contracting activity (N0018919D0004). Vadum Inc.,* Raleigh, North Carolina, is awarded a $9,413,901 cost-plus-fixed-fee, level of effort, research and development contract with a five-year period of performance, to procure engineering support services. Technical instructions will be issued in accordance with the Statement of Work for this contract to support the Reactive Electronic Attack Measures project. Work will be performed in Raleigh, North Carolina, and will be completed by February 2024. Fiscal 2019 research, development, test and evaluation (Navy) funding in the amount of $1,000,000 will be obligated at time of award and will not expire at the end of the current fiscal year. This contract was not competitively procured in accordance with 10 U.S. Code 2304(c)(1) - only one responsible source and no other services will satisfy agency requirements. The Naval Surface Warfare Center, Crane Division, Crane, Indiana, is the contracting activity (N00164-19-C-WS30). Lockheed Martin, Rotary and Mission Systems, Moorestown, New Jersey, is awarded an $8,242,834 cost-plus-incentive-fee modification to previously awarded contract (N00024-15-C-5151) to exercise options for ship integration and test of the Aegis Weapon System (AWS) for AWS Baselines through Advanced Capability Build 16. Work will be performed in Camden, New Jersey (43 percent); Pascagoula, Mississippi (25 percent); Norfolk, Virginia (12 percent); Everett, Washington (10 percent); Virginia Beach, Virginia (6 percent); San Diego, California (3 percent); and Washington, District of Columbia (1 percent), and is expected to be completed by September 2024. Fiscal 2015 shipbuilding and conversion (Navy); and 2019 other procurement (Navy) funding in the amount of $8,242,834 will be obligated at the time of award. No contract funds will expire at the end of the current fiscal year. The Naval Sea Systems Command, Washington, District of Columbia, is the contracting activity. ARMY T&H Services LLC,* Juneau, Alaska, was awarded a $26,468,671 cost-plus-fixed-fee contract for base operations support services. Bids were solicited via the internet with six received. Work will be performed in Fort Carson, Colorado, with an estimated completion date of Feb. 18, 2020. Fiscal 2019 operations and maintenance Army funds in the amount of $5,019,250 were obligated at the time of the award. U.S. Army Mission and Installation Contracting Command, Fort Carson, Colorado, is the contracting activity (W911RZ-19-C-0002). Wood Environment & Infrastructure Solutions Inc., Blue Bell, Pennsylvania, was awarded a $12,000,000 firm-fixed-price contract for hazardous toxic and radiologic waste consulting services. Bids were solicited via the internet with four received. Work locations and funding will be determined with each order, with an estimated completion date of Feb. 19, 2024. U.S. Army Corps of Engineers, Concord, Massachusetts, is the contracting activity (W912WJ-19-D-0002). * Small business https://dod.defense.gov/News/Contracts/Contract-View/Article/1760766/